Genetic Approaches

CCR5Δ32 Hematopoietic Stem Cell Transplantation: The Berlin, London, and Düsseldorf HIV Cures

1. Introduction: The Exceptional Cases That Redefined HIV Cure Research Combination antiretroviral therapy (ART) suppresses HIV-1 replication, restores CD4+ T-cell…

Genetically Modified CCR5 Cells: Lessons from the He Jiankui Case

1. Introduction: The Intersection of CRISPR, HIV, and the Human Germline The advent of CRISPR-Cas9 genome editing technology precipitated a…

CRISPR-Cas9 Against HIV: Excising Viral DNA from the Genome of Infected Cells

1. Introduction: The Unmet Need for an HIV Cure Since the identification of the human immunodeficiency virus (HIV) in the…